TBHP-mediated highly efficient dehydrogenative cross-oxidative coupling of methylarenes with acetanilides

• Cui Chen,
• Weibing Liu and
• Peng Zhou

Beilstein J. Org. Chem. 2016, 12, 2250–2255, doi:10.3762/bjoc.12.217

• Cui Chen Weibing Liu Peng Zhou College of Chemical Engineering, Guangdong University of Petrochemical Technology, 2 Guandu Road, Maoming 525000, P. R. China. Fax: +86-668-2923575; Tel: +86-668-2923444 10.3762/bjoc.12.217 Abstract A TBHP-mediated dehydrogenative cross-oxidative-coupling approach

• C–N bonds. Besides, this conversion is an important complement to the conventional C–N forming strategies. Keywords: dehydrogenative cross oxidative coupling; methyl arenes; N-arylbenzamides; TBHP; Introduction Recently, amides have attracted more and more attention due to their extensive

• ketoximes [13], the C–N cross coupling between aromatic amides or amines and aryl(pseudo)halides [14][15] or aldehydes [16][17][18][19][20]. However, to the best of our knowledge, the studies of dehydrogenative cross-oxidative-coupling reactions between methylarenes and amines for the formation of amides